VGM: Fully automated AI-assisted diagnostics of brain MRI

The start-up VGMorph from Mülheim an der Ruhr wants to improve the health and quality of life of patients in the long term. To do this, it uses an innovative approach for the precise analysis of MRI scans using 3D brain volumetry. The method for this is called voxel-guided morphometry (VGM) and compares a single MRI of a patient with a healthy comparison cohort or several MRIs of the same patient intraindividually over time. The results are visualized three-dimensionally, quantified in absolute terms and statistically evaluated.

The founders of the company, physicist Dr. Andreas Dabringhaus, neurologist Dr. Matthias Kraemer and business graduate Axel Lauterborn are among the pioneers of the methods and are now members of the ZENIT network.

Different groups can be considered as users:

👉 Clinics and practices: Support in the evaluation of serial MRIs of patients with neurological or neurosurgical diseases
👉 Pharmaceutical companies: Support in clinical trials to assess the efficacy and development of new drugs or therapeutic procedures.
👉 Universities and research institutions: Collaborations to investigate structural changes in the brain in human or animal studies.
👉 MRI/CT machine manufacturers and app developers: Integration of VGM software into diagnostic devices

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MRI-based morphometric structural changes correlate with histopathology in experimental autoimmune encephalomyelitis

Magnetic resonance imaging (MRI) and neurohistopathology are important correlates for evaluation of disease progression in multiple sclerosis (MS).

Venous Diameter Changes in Chronic Active Multiple Sclerosis Lesions

To investigate the temporal evolution of venous diameter in chronic active and nonenhancing shrinking multiple sclerosis (MS) lesions in a longitudinal magnetic resonance imaging (MRI) study including susceptibility‐weighted images (SWI).

Individual Assessment of Brain Tissue Changes in MS and the Effect of Focal Lesions on Short-Term Focal Atrophy Development in MS: A Voxel-Guided Morphometry Study

We performed voxel-guided morphometry (VGM) investigating the mechanisms of brain atrophy in multiple sclerosis (MS) related to focal lesions.

Mobilisation of hematopoietic CD34+ precursor cells in patients with acute stroke is safe–results of an open-labeled non randomized phase I/II trial

Regenerative strategies in the treatment of acute stroke may have great potential.

Chronic changes in brain volume in MS patients: individual analysis and group data as assessed using Voxel-Guided Morphometry

DOI: 10.1016/S1053-8119(09)70453-7 Find more publications at: https://vgmorph.com/publications/

Delayed shrinkage of the brain after ischemic stroke: preliminary observations with voxel-guided morphometry

The most important effect of cerebral ischemia is brain infarction. In this magnetic resonance imaging (MRI) study, the authors aimed at assessing postischemic brain atrophy.

VGMorph News

VGMorph now member at the ZENIT network